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Recently, Louisville has blossomed as a major gathering place for the health care and health-related sciences industrial sectors. Louisville has been key to breakthroughs in heart and hand surgery as well as cancer healing. Several of the earliest man made coronary heart transplants were performed in Louisville. Louisville's flourishing downtown medical research grounds comprises of a new $88 million rehab community, and a health and wellbeing sciences analysis and commercialization recreation area that, in partnership with the University of Louisville, has lured nearly 80 major experts and scientists. Louisville is also home to Humana, one particular of the nation's major health insurance policy organizations.

Louisville is home to several major companies and establishments.